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English化学与生命健康交叉研究中心
孔望清
教授，博士生导师
课题组主页：http://wqkong.whu.edu.cn
研究方向
1）金属有机化学：过渡金属不对称催化
2）自由基化学：发展新的策略实现自由基反应的立体选择性控制
3）开展具有生物活性天然产物和药物分子的高效合成研究
教育与研究经历
2017.04-至今 爱彩人彩票登录，教授
2014.10-2017.03 瑞士洛桑联邦理工大学 (EPFL)，博士后，导师： Jieping Zhu
2011.09-2014.09 瑞士苏黎世大学 (UZH)，博士后，导师： Cristina Nevado
2006.09-2011.06 浙江大学，博士，导师：麻生明教授（中国科学院院士）
荣誉与奖励
诺华制药博士后奖学金（2012）
苏黎世大学博士后基金（2011）
浙江省优秀毕业生（2011）
宝钢优秀学生奖（2009）
Publications
22. Kuai Wang, Zhengtian Ding, Zhijun Zhou, and Wangqing Kong*. Ni-Catalyzed Enantioselective Reductive Diarylation of Activated Alkenes by Domino Cyclization/Cross-Coupling. J. Am. Chem. Soc., 2018, 140, 12364-12368.
21. Yuanyuan Ping, Yuxiu Li, Jieping Zhu*, Wangqing Kong*. Construction of Quaternary Stereocenters by Palladium‐Catalyzed Carbopalladation‐Initiated Cascade Reactions. Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.201806088.
20. Yuxiu Li, Kuai Wang, Yuanyuan Ping, Yifan Wang, and Wangqing Kong*. Nickel-Catalyzed Domino Heck Cyclization/Suzuki Coupling for the Synthesis of 3,3-Disubstituted Oxindoles. Org. Lett. 2018, 20, 921−924 (Highlighted by Synfacts, 2018, 14(4), 410)
19. Kuai Wang, Wangqing Kong*. Recent Advances in Transition Metal Catalyzed Asymmetric Radical Reactions. Chin. J. Chem. 2018, 36, 247-256. (Cover Story)
Before independent work:
18. Wangqing Kong, Qian Wang, Jieping Zhu*. Water as hydride source in palladium-catalyzed enantioselective reductive Heck reaction. Angew. Chem. Int. Ed. 2017, 56, 3987-3991. (Chosen by the Editors as a “Hot Paper”) (Highlighted by Synfacts, 2017, 13(5), 495) (Highly Cited Paper)
17. Wangqing Kong, Qian Wang, Jieping Zhu*. Switchable synthesis of diversely functionalized oxindoles enabled by migratory insertion of isocyanide to a transient σ-alkylpalladium(II) complex. Angew. Chem. Int. Ed. 2016, 55, 9714-9718.
16. Wangqing Kong, Qian Wang, Jieping Zhu*. Palladium-catalyzed enantioselective domino heck/intermolecular C-H bond functionalization: Development and application to the synthesis of (+)-esermethole. J. Am. Chem. Soc. 2015, 137, 16028-16031. (Highlighted by Synfacts, 2016, 12(3), 274.)
15. Wangqing Kong, Noelia Fuentes, Andres García-Domínguez, Estíbaliz Merino, Cristina Nevado*. Stereoselective synthesis of highly functionalized indanes and dibenzocycloheptadienes via complex radical cascades. Angew. Chem. Int. Ed. 2015, 54, 2487-2491.
14. Noelia Fuentes, Wangqing Kong, Luis Fernández-Sánchez, Estíbaliz Merino, Cristina Nevado*. Cyclization cascades via N-amidyl radicals toward highly functionalized heterocyclic scaffolds. J. Am. Chem. Soc. 2015, 137, 964-973. (Highly Cited Paper)
13. Wangqing Kong, Estíbaliz Merino, Cristina Nevado*. Arylphosphonylation and arylazidation of activated alkenes. Angew. Chem. Int. Ed. 2014, 53, 5078-5082. (Chosen by the Editors as a “Hot Paper”) (Highly Cited Paper)
12. Wangqing Kong, Estíbaliz Merino, Cristina Nevado*. Divergent reaction mechanism in the aminofluorination of alkenes. CHIMIA International Journal for Chemistry, 2014, 68, 430-435.
11. Wangqing Kong, Maria Casimiro, Noelia Fuentes, Estíbaliz Merino, Cristina Nevado*. Metal-free aryltrifluoromethylation of activated alkenes. Angew. Chem. Int. Ed. 2013, 52, 13086-13090. (Highly Cited Paper)
10. Wangqing Kong, Maria Casimiro, Estibaliz Merino, Cristina Nevado*. Copper-catalyzed 1-pot trifluoromethylation/arylmigration/desulfonylation and Csp2-N bond formation of conjugated tosyl amides. J. Am. Chem. Soc. 2013, 135, 14480-14483. (Highly Cited Paper)
9. Wangqing Kong, Pascal Feige, Teresa de Haro, Cristina Nevado*. Regio- and enantioselective aminofluorination of alkenes. Angew. Chem. Int. Ed. 2013, 52, 2469-2473. (Highlighted by Synfacts 2013, 9 (4), 371 and Organic Chemistry Portal 2014, March 17.) (Highly Cited Paper)
8. Wangqing Kong, Youai Qiu, Xue Zhang, Chunling Fu, Shengming Ma*. Exclusive 1,2-aryl shift in Platinum(II) chloride-catalyzed cyclization of 1-(indol-2-yl)-2,3-allenols. Adv. Synth. Catal. 2012, 354, 2339-2347.
7. Wangqing Kong, Chunling Fu, Shengming Ma*. Efficient synthesis of carbazoles via PtCl2-catalyzed RT cyclization of 1-(indol-2-yl)-2,3-allenols: scope and mechanism. Org. Biomol. Chem. 2012, 10, 2164-2173.
6. Wangqing Kong, Chunling Fu, Shengming Ma*. General Au-catalyzed benzannulation towards naturally occurring carbazole alkaloids from methoxypropadiene. Chem. Eur. J. 2011, 17, 13134-13137.
5. Wangqing Kong, Binjie Guo, Chunling Fu, Shengming Ma*. An efficient approach to 2-bromoalken-3-ols by regioselective bromohydroxylation reaction of simple allenes with NBS. Eur. J. Org. Chem. 2011, 2278-2285.
4. Wangqing Kong, Chunling Fu, Shengming Ma*. An efficient synthesis of polysubstituted naphthalene derivatives by gold-catalyzed cyclization of 1-arylalka-2,3-dienyl acetates. Eur. J. Org. Chem. 2010, 6545-6555.(Cover Story)
3. Wangqing Kong, Jie Cui, Yihua Yu, Guofei Chen, Chunling Fu, Shengming Ma*. PtCl4-catalyzed cyclization reaction of β-allenols in the presence of indole. Org. Lett. 2009, 11, 1213-1216.
2. Wangqing Kong, Chunling Fu, Shengming Ma*. An efficient synthesis of carbazoles from PtCl2-catalyzed cyclization of 1-(indol-2-yl)-2,3-allenols. Chem. Commun. 2009, 4572–4574.
1. Wangqing Kong, Chunling Fu, Shengming Ma*. Indium and zinc-mediated Barbier-type addition reaction of 2,3-allenals with allyl bromide: an efficient synthesis of 1,5,6-alkatrien-4-ols. Org. Biomol. Chem. 2008, 6, 4587–4592.
专利
1.一种合成咔唑类化合物的方法，专利号：ZL 200910099482.X
2.一种合成咔唑类生物碱 Siamenol 的方法，专利号：ZL 201110283659.9
3.一种合成天然咔唑类生物碱的制备方法，专利号：ZL 201110283147.2
4.一种合成咔唑类化合物的方法，专利号：ZL 201210516430.X
课题组招贤纳才
博士后
薪酬待遇：工资及福利待遇根据武汉大学相关规定从优考虑（五险一金，解决户口和子女入学等问题）；并根据工作业绩额外发放津贴（预计年薪25-30万元，具体薪资待遇面议）；可作为负责人申请博后基金、国家青年基金、和湖北省相关基金。博士后期间特别优秀者可协助申请武汉大学正式教师（非独立成组）。
职位要求：
1）有机化学博士，有写作和发表英文科技论文经历。
2）有团队精神，工作踏实，有责任感，易沟通。
3）有金属有机化学（特别是过渡金属不对称催化）或自由基化学研究经历者优先考虑。
请发送个人简历、主要研究成果等相关资料到：wqkong@whu.edu.cn
研究助理2-3名
薪酬待遇：将提供具有竞争力的薪酬待遇，并根据工作业绩额外发放津贴，可优先报考硕士或者博士研究生。
职位要求：
1）本科或硕士学位，化学相关专业，熟悉常规有机化学实验技术和操作。
2）工作踏实，有责任感，具有良好的沟通能力和合作精神。
3）英语良好，能独立阅读英文文献。
请发送个人简历及其他能证明本人能力的相关资料到：wqkong@whu.edu.cn
研究生
欢迎全国的优秀学子报考本小组的博士或硕士研究生。要求专业基础扎实，工作踏实，有团队精神，具有良好的沟通能力。我们将提供具有竞争力的待遇，并根据工作业绩额外发放津贴。有意者请直接邮件联系wqkong@whu.edu.cn